For the last 20 years, Dr. Frank Berenson and Dr. Robert Flamini have been involved in multiple clinical research trials. The emphasis has been primarily in epilepsy and headache medicine with different medications, most of which are currently in the market for management of these conditions. The acquisition of data through clinical trials, along with the voluntary participation of our patients and families, has been instrumental in the advancement of clinical practice.
PANDA Neurology and Atlanta Headache Specialists has a dedicated full-time clinical research coordinator. We conduct multicenter trials and investigator-initiated protocols. Information on most of the clinical trials is available at www.clinicaltrials.gov.
PANDA Neurology and Atlanta Headache Specialists are actively involved in several research studies to investigate medications (not marketed), as well as to study current medications for new purposes. Below is a list of the current drug research protocols in place at PANDA Neurology and Atlanta Headache Specialists.
1. A study with an Extension Phase to Evaluate the Safety, Tolerability, and Exposure-Efficacy Relationship Of Perampanel Oral Suspension when Administered as an Adjunctive Therapy in Pediatric Subjects (Age 4 to less than 12 years) with Inadequately Controlled Partial-Onset Seizures. (Enrollment Open).
2. A study to Evaluate the Safety, Tolerability, and Exposure-Efficacy of Perampanel Oral Suspension when Administered as an Adjunctive Therapy in Pediatric Subjects with Inadequately Controlled Partial-Onset Seizures or Generalized Tonic-Clonic Seizures. (Enrollment Open).
1. A study to Evaluate the Efficacy and Safety of ALD403 Administered Intravenously in Patients with Chronic Migraine. (Enrollment Open).
2. A Study to Assess the Long-term Safety and Efficacy of AMB 334 in Chronic Migraine Prevention. (Enrollment Closed)
1. A phase IV, Prospective, Observational, Multicenter Study Evaluating the Effectiveness and Safety of Dysport (abobotulinumtoxina) in Pediatric Lower Limb Spasticity. (Enrollment Open).
1. Physician Sponsored Expanded IND for the use of Cannabidiol (CBD) in pediatric intractable epilepsy. (Enrollment Closed).
2. A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults with Dravet. (Enrollment Closed).
3. A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P;CBD) as Adjunctive Treatment for Seizures Associated with Lennox-Gastaut Syndrome in Children and Adults. (Enrollment Closed)
4. An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Young Adults with Dravet or Lennox-Gastaut Syndrome. (Enrollment Closed)
5. GA State sponsored Expanded IND for the use of Cannibidiol (CBD) in pediatric epilepsy (excluding Dravet and Lennox-Gastaut Syndrome). (Enrollment Closed)
All drug study protocols initiated by our practice follow very strict criteria. Clinical trials are federally regulated and approved by an Institutional Review Board (IRB), which safeguards the rights of patients participating in the drug studies.
Participation is entirely voluntary and completely confidential. Study criteria must be met before participation is approved. Most of the costs for participants are covered, including physical exams, laboratory work, follow-up visits, and study medication. In some cases, additional financial compensation is provided to participants.
If you have an interest in any of the studies above for you, your child or a patient, contact our Research Manager, Wes Williams at email@example.com. You may also discuss any of the protocols with one of the providers at PANDA Neurology and Atlanta Headache Specialists.